Inherited Diseases and Traits: PKD
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Testing Fee: $38/feline
Turnaround Time: 10 working days |
Polycystic Kidney Disease (PKD) is inherited as an autosomal dominant disorder among Persian, Himalayan, Exotics and Persian-related cats. Characterized by the formation of cysts on the kidneys, PKD could lead to eventual renal failure and possible death.
PKD is dominant; therefore, heterozygotes (those possessing one copy of the mutation) will likely be clinically affected. When bred to genotypically normal cats, heterozygotes will still likely produce clinically affected offspring 50% of the time.
Cat owners can collect DNA samples themselves quickly and painlessly using buccal (cheek) swabs for collecting loose skin cells. Cats of any age can be tested.
We will provide a detailed DNA report showing the cat's genotype for PKD. The possible genotypes include: NN (2 copies of the normal allele) NP Heterozygote (1 normal copy and 1 copy of the PKD mutation), or PP (2 copies of the PKD mutation ). Please note that it is expected that PP genotypes will likely die during gestation and therefore it is very unlikely that a live cat will test PP.
Review the schematic table below to see how PKD is inherited.
If you have additional questions about testing please feel email us at contact@catdna.org.
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